I have an old Accucraft K-27. An all metal loco of a similar weight to your C-18. And that is the important bit - you need to ensure the ESC, separate or part of a DCC sound/ESC, you use is capable of handling the volts/amps a heavy loco can draw under full load. My conversion was carried out by Fosworks here in the UK and has a 100 watt ESC fitted, 30 watt was considered borderline. Loco draws, say, 5 amps using 18 v = 90 watt. So you have a bit of headroom on a motor that will probably have a max draw of 3 amps.
Battery packs ? My large locos use 18v NiMH AA packs. However if you are wanting very long run times, with all the flashing lights, bells and whistles going (and a smke generator ?), you might want to consider sub-C size. As others have said you may want to go for the Eneloop NiMH.
Next, as mentioned, your loco is all metal. Any RX should have the ariel component mounted externaly on an upper surface of the loco. Your tender is like a Faraday cage if the coal load has a metal tray. Plastic locos you can get away without.
Sound - my old K-27 has a wonderful old Sierra card fitted, with clever bits that get over its issues with the ESC's PWM output. Nowadays, however, my preference is to fit ESU make DCC cards with their own ESC's incorporated to my locos. Again make sure the wattage or amps rating is sufficient. ESU's current 5XL type should do for your loco. It can handle 5 amps. ESU has a sound library that covers most D&RGW NG loco types. Again you may prefer a more traditional "DC" set up using a Phoenix sound card or suchlike.
Finally TX & RX - If you go for a DCC sound/ESC set up you can get hand held TX's and DCC compatible RX combos that will allow you to make fuller use of a DCC card's features and capabilities in a battery/rc set up. Again I source from Fosworks here in the UK.
Oh, and it all fits in the tender. My old K-27 has a simple bus bar under the cab that the electrical bits in the loco conect to, inc' its big Pitman motor and gearbox. I just have 2 wires, from the ESC, going in here with a JST connector so I can separate the tender. I understand Accucraft may have upgraded this arrangement, but the basics are the same. Hope this info helps.
Max